Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells
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منابع مشابه
Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells
Mitofusin 2 (Mfn2), mitochondrial outer membrane protein which is involved in rearrangement of these organelles, was first described in pathology of hypertension and diabetes, and more recently much attention is paid to its functions in Charcot-Marie-Tooth type 2A neuropathy (CMT2A). Here, cellular energy metabolism was investigated in mouse embryonic fibroblasts (MEF) differing in the presence...
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Mitofusin 2 (Mfn2), mitochondrial outer membrane protein which is involved in its rearrangement, was first described in pathology of hypertension and diabetes, but nowadays much attention is paid to its functions in Charcot-MarieTooth type 2A neuromyopathy (CMT2A). Here, effects of Mfn2 deficiency on cell metabolism in the presence or absence of Mfn1 were investigated. Experiments were performe...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0134162